Syphilis is a sexually transmitted disease caused by spirochetal bacteria Treponema pallidum subspecies pallidum. The primary route of transmission of syphilis is through sexual contact however it may also be transmitted from mother to fetus during pregnancy.
The signs and symptoms of syphilis vary depending on which of the four stages it presents in (primary, secondary, latent, and tertiary). The primary stage typically presents with a single chancre, secondary syphilis with a diffuse rash, latent with little to no symptoms, and tertiary with gummas, neurological, or cardiac symptoms. Syphilis is believed to have infected 12 million people worldwide. |
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